This paper presents the study of CogState and the brief computerized cognitive test battery it offers in a range of distinct cognitive functions. The tests use novel visual and verbal stimuli to ensure assessments are culture-neutral and not limited by a subject’s level of education, ethnicity or socio-economic background.
Whilst these tests can and are used to determine the effect of drugs, devices and other interventions in cognition in many different conditions, diseases and disorders, our application of test batteries involved otherwise healthy volunteers in the workplace.
The attraction of CogState is in its ability to be used in significantly less invasive methods than existing methods of drug, alcohol, and fatigue assessments and at the same time minimizing practice or learning effects by participants. An examination of criterion and construct validity of the brief computerized cognitive test battery is compared to more conventional cognitive test battery and the degree of sensitivity to the effects of alcohol, fatigue and certain types of drugs.
Tests begin by taking a baseline measurement from a subject who is then periodically re-tested in order to detect cognitive change in a number of domains including; psychomotor function and speed of processing, visual attention, executive function and social-emotional cognition.
Fredrickson A, Snyder PJ, Cromer C, Thomas E , Lewis M, Maruff P. (in press) The use of effect sizes to characterise the nature of cognitive change in psychopharmacological studies: An example with scopolamine. Human Psychopharmacol.